[1]王建秋,卢山.绝经后糖尿病患者椎体骨质量评分与骨密度的关系[J].国际内分泌代谢杂志,2024,44(01):9-13.[doi:10.3760/cma.j.cn121383-20230212-02020]
　Wang Jianqiu,Lu Shan.Relationship between vertebral bone quality score and bone density in postmenopausal women with diabetes[J].International Journal of Endocrinology and Metabolism,2024,44(01):9-13.[doi:10.3760/cma.j.cn121383-20230212-02020]
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绝经后糖尿病患者椎体骨质量评分与骨密度的关系()
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
44
期数:
2024年01期
页码:
9-13
栏目:
论著
出版日期:
2024-01-20

文章信息/Info

Title:
Relationship between vertebral bone quality score and bone density in postmenopausal women with diabetes
作者:
王建秋; 卢山
天津医科大学朱宪彝纪念医院、天津市内分泌研究所、国家卫生健康委员会激素与发育重点实验室、天津市代谢性疾病重点实验室,天津 300134
Author(s):
Wang Jianqiu;  Lu Shan
NHC Key Laboratory of Hormones and Development, Tianjin Key Laboratory of Metabolic Diseases, Chu Hsien-I Memorial Hospital & Tianjin Institute of Endocrinology, Tianjin Medical University, Tianjin 300134, China
关键词:
目的 探讨腰椎磁共振成像(MRI)椎体骨质量(VBQ)评分评估糖尿病绝经后女性骨密度的应用价值。方法 回顾性分析2019年6月至2022年12月在天津医科大学朱宪彝纪念医院诊治的糖尿病绝经后女性145例; 根据骨密度结果分为正常组、骨量减少组和骨质疏松组。通过腰椎MRI T1加权像测量VBQ评分; Image J软件计算L3椎体右侧椎旁肌脂肪浸润分数。比较3组各参数的差异; 受试者工作特征(ROC)曲线分析VBQ评分诊断骨质疏松的效能; 分析VBQ评分和T值及各参数的相关性。结果 VBQ评分骨质疏松组>; 骨量减少组>; 正常组(P均<; 0.05)。L3椎体右侧椎旁肌脂肪浸润分数骨质疏松组大于骨量减少组、正常组(P均<; 0.05)。VBQ评分诊断骨质疏松的ROC曲线下面积为0.830。VBQ评分与L3椎体右侧椎旁肌脂肪浸润分数呈显著弱正相关。VBQ评分与双能X线吸收仪(DXA)最低T值呈显著中度负相关。结论 VBQ评分对糖尿病绝经后女性骨密度的评估可能有一定的价值。
Keywords:
Vertebral bone quality score;  Bone density;  Type 2 diabetes mellitus;  Postmenopausal women
DOI:
10.3760/cma.j.cn121383-20230212-02020
摘要:
目的 探讨腰椎磁共振成像(MRI)椎体骨质量(VBQ)评分评估糖尿病绝经后女性骨密度的应用价值。方法 回顾性分析2019年6月至2022年12月在天津医科大学朱宪彝纪念医院诊治的糖尿病绝经后女性145例,根据骨密度结果分为正常组、骨量减少组和骨质疏松组。通过腰椎MRI T1加权像测量VBQ评分,Image J软件计算L3椎体右侧椎旁肌脂肪浸润分数。比较3组各参数的差异,受试者工作特征(ROC)曲线分析VBQ评分诊断骨质疏松的效能,分析VBQ评分和T值及各参数的相关性。结果 VBQ评分骨质疏松组>骨量减少组>正常组(P均<0.05)。L3椎体右侧椎旁肌脂肪浸润分数骨质疏松组大于骨量减少组、正常组(P均<0.05)。VBQ评分诊断骨质疏松的ROC曲线下面积为0.830。VBQ评分与L3椎体右侧椎旁肌脂肪浸润分数呈显著弱正相关。VBQ评分与双能X线吸收仪(DXA)最低T值呈显著中度负相关。结论 VBQ评分对糖尿病绝经后女性骨密度的评估可能有一定的价值。
Abstract:
Objective To explore the value of vertebral bone quality(VBQ)score of lumbar spine MRI in evaluating bone density of postmenopausal women with diabetes.Methods This was a retrospective analysis of 145 postmenopausal women with diabetes admitted to our hospital from June 2019 to December 2022. According to the results of bone density, they were divided into normal bone, osteopenia, and osteoporosis groups. The VBQ score was measured by T1-weighted MRI of the lumbar spine. The fat infiltration fraction of the right paraspinal muscle at L3 was calculated through Image J software. The differences of parameters among the three groups were compared. The receiver operating characteristic(ROC)curve was used to evaluate the efficiency of VBQ score in the diagnosis of osteoporosis. The correlation between VBQ score and T value and various parameters were analyzed.Results The VBQ score of osteoporosis group was higher than osteopenia group and normal group(all P<0.05). The fat infiltration fraction of L3 right paraspinal muscle in osteoporosis group was higher than osteopenia group and normal group(all P<0.05). The area under the ROC curve for diagnosing osteoporosis by VBQ score was 0.830. The VBQ score was significantly positively correlated with the fat infiltration fraction of the right paraspinal muscle at L3. The VBQ score was significantly and moderately negatively correlated with the lowest T value of DXA.Conclusion The VBQ score may be valuable in evaluating bone density of postmenopausal women with diabetes.

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备注/Memo

备注/Memo:
基金项目:天津市医学重点学科(专科)建设项目资助(TJYXZDXK-032A)
通信作者:卢山,Email:lushan1213@sina.com
更新日期/Last Update: 2024-03-20