[1]陆东宁,徐加杰,葛明华.甲状腺球蛋白在分化型甲状腺癌复发转移诊治中的研究进展[J].国际内分泌代谢杂志,2022,42(06):465-468.[doi:10.3760/cma.j.cn121383-20210930-09092]
　Lu Dongning,Xu Jiajie,Ge Minghua..Research progress of thyroglobulin in the diagnosis and treatment of recurrence and metastasis of differentiated thyroid cancer[J].International Journal of Endocrinology and Metabolism,2022,42(06):465-468.[doi:10.3760/cma.j.cn121383-20210930-09092]
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甲状腺球蛋白在分化型甲状腺癌复发转移诊治中的研究进展()
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
42
期数:
2022年06期
页码:
465-468
栏目:
综述
出版日期:
2022-11-20

文章信息/Info

Title:
Research progress of thyroglobulin in the diagnosis and treatment of recurrence and metastasis of differentiated thyroid cancer
作者:
陆东宁1; 徐加杰2; 3; 葛明华1; 2; 3
1浙江中医药大学第二临床医学院,杭州 310053; 2浙江省人民医院头颈外科 耳鼻咽喉-头颈外科中心 杭州医学院附属人民医院 310014; 3浙江省内分泌腺体疾病诊治研究重点实验室,杭州 310014
Author(s):
Lu Dongning1;  Xu Jiajie2; 3;  Ge Minghua1; 2; 3.
1Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou 310053, China; 2Department of Head and Neck Surgery, Center of Otolaryngology-Head and Neck Surgery, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou 310014, China; 3Key Laboratory of Endocrine Gland Diseases of Zhejiang Province, Hangzhou 310014, China
关键词:
分化型甲状腺癌;  甲状腺球蛋白;  复发;  转移
Keywords:
Differentiated thyroid carcinoma;  Thyroglobulin;  Recurrence;  Metastasis
DOI:
10.3760/cma.j.cn121383-20210930-09092
摘要:
分化型甲状腺癌(differentiated thyroid carcinoma,DTC)的复发转移是临床诊治的难点,血清甲状腺球蛋白(thyroglobulin,Tg)、淋巴结细针穿刺洗脱液甲状腺球蛋白检测(thyroglobulin measurement in fine-needle aspiration, FNA-Tg)与其他创新性的Tg检测手段在复发转移患者的诊断、治疗和随访过程中都具有重要意义,而如何选择最合适的Tg检测模式和确定最佳临界值依然存在一定争议,需要进一步研究。本文将对这些异议进行综述并分析,为临床提供一些新的研究思路。
Abstract:
The recurrence and metastasis of differentiated thyroid carcinoma(DTC)has always been the key of clinical treatment. The detection of thyroglobulin(TG), thyroglobulin measurement in fine-needle aspiration(FNA-Tg)and other innovative Tg assays can provide reference for the diagnosis, treatment and follow-up of recurrence and metastasis. However, the selection of the most appropriate Tg assay modality and the determination of the optimal threshold value remain controversial and require further study.In this paper, these objections are reviewed and analyzed to provide some new research ideas for clinical purposes.

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备注/Memo

备注/Memo:
通信作者:葛明华,Email: gemingh@163.com
基金项目:国家自然科学基金青年科学基金项目(81802674); 浙江省自然科学基金(LY21H160049); 浙江省医药卫生科学研究基金(2021KY482); 浙江省教育厅一般科研项目(Y202146111)
更新日期/Last Update: 2022-12-01