[1]高忠爱,杨波,郑妙艳,等.糖尿病合并大量蛋白尿的中西医治疗策略[J].国际内分泌代谢杂志,2021,41(06):583-586.[doi:10.3760/cma.j.cn121383-20210930-09088]
　Gao Zhongai,Yang Bo,Zheng Miaoyan,et al.Treatment strategies of traditional Chinese and western medicine in diabetic patients with overt proteinuria[J].International Journal of Endocrinology and Metabolism,2021,41(06):583-586.[doi:10.3760/cma.j.cn121383-20210930-09088]
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糖尿病合并大量蛋白尿的中西医治疗策略()
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
41
期数:
2021年06期
页码:
583-586
栏目:
专家论坛
出版日期:
2021-12-20

文章信息/Info

Title:
Treatment strategies of traditional Chinese and western medicine in diabetic patients with overt proteinuria
作者:
高忠爱1; 杨波2; 郑妙艳1; 贾俊亚3; 常宝成1
1天津医科大学朱宪彝纪念医院、天津市内分泌研究所、国家卫生健康委员会激素与发育重点实验室、天津市代谢性疾病重点实验室 300134; 2天津中医药大学第一附属医院 300192; 3天津医科大学总医院 300052
Author(s):
Gao Zhongai1;  Yang Bo2;  Zheng Miaoyan1;  Jia Junya3;  Chang Baocheng1.
1NHC Key Laboratory of Hormones and Development, Tianjin Key Laboratory of Metabolic Diseases, Chu Hsien-I Memorial Hospital & Tianjin Institute of Endocrinology, Tianjin Medical University, Tianjin 300134, China; 2First Teaching
关键词:
糖尿病肾脏病;  大量蛋白尿;  中西医;  治疗
Keywords:
Diabetic kidney disease;  Overt proteinuria;  Traditional Chinese and western medicine;  Treatment
DOI:
10.3760/cma.j.cn121383-20210930-09088
摘要:
糖尿病肾脏病(DKD)是2型糖尿病严重的微血管并发症,已成为导致终末期肾病的首要病因。DKD患者一旦进展到大量蛋白尿阶段,疾病已不可逆转,预后较差。而合理规范的治疗可降低尿蛋白,延缓肾病进展。目前一些新型降糖药能减少DKD患者尿蛋白,尤其是钠-葡萄糖协同转运蛋白2抑制剂,能降低DKD患者肾脏复合终点风险; 中医中药在延缓DKD合并大量蛋白尿患者肾功能恶化、改善临床症候方面有一定的优势。本文将根据国内外相关研究报道以及自身的临床体会对糖尿病合并大量蛋白尿的中西医治疗策略进行讨论。
Abstract:
Diabetic kidney disease(DKD)is a serious microvascular complication of type 2 diabetes mellitus, and it has become the major cause of end-stage renal disease. Once DKD progresses to overt proteinuria, it is irreversible and the prognosis is poor. Reasonable and standardized treatment can reduce urinary protein and delay the progression of the disease. At present, some new hypoglycemic drugs can reduce urine protein, especially sodium-glucose cotransporter 2 inhibitors, which can reduce the risk of renal composite endpoint in patients with DKD; Traditional Chinese medicine has an advantage in delaying the deterioration of renal function and and improving clinical symptoms in patients with DKD. This paper will discuss potential treatment strategies of traditional Chinese and western medicine in diabetic patients with overt proteinuria based on relevant research and our own clinical experience.

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备注/Memo

备注/Memo:
基金项目:国家重点研发计划(2018YFC1314000); 国家自然科学基金项目(81774043,82074253); 天津市科技计划项目(17ZXMFSY00140)
通信作者:郑妙艳,Email: myzheng73@163.com; 常宝成,Email: changbc1970@126.com
更新日期/Last Update: 2021-12-10