[1]王书畅,潘慧,朱惠娟.重组人生长激素联合雌激素在Turner综合征中的治疗进展[J].国际内分泌代谢杂志,2017,37(02):116-119.[doi:10.3760/cma.j.issn.1673-4157.2017.02.012]
　Wang Shuchang,Pan Hui,Zhu Huijuan..Therapeutic prospects of recombinant human growth hormone combined with estrogen on Turner syndrome[J].International Journal of Endocrinology and Metabolism,2017,37(02):116-119.[doi:10.3760/cma.j.issn.1673-4157.2017.02.012]
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重组人生长激素联合雌激素在Turner综合征中的治疗进展()
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
37
期数:
2017年02期
页码:
116-119
栏目:
综述
出版日期:
2017-03-20

文章信息/Info

Title:
Therapeutic prospects of recombinant human growth hormone combined with estrogen on Turner syndrome
作者:
王书畅; 潘慧; 朱惠娟
100730 北京,中国医学科学院,北京协和医学院,北京协和医院内分泌科,国家卫生和计划生育委员会内分泌重点实验室
Author(s):
Wang Shuchang;  Pan Hui;  Zhu Huijuan.
Key Laboratory of Endocrinology, National Health and Family Planning Commission, Department of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China
关键词:
Turner综合征;  重组人生长激素;  雌激素
Keywords:
Turner syndrome;  Recombinant human growth hormone;  Estrogen
DOI:
10.3760/cma.j.issn.1673-4157.2017.02.012
摘要:
Turner综合征是由X染色体数量和结构异常导致的一种常见性染色体相关疾病,矮身材及性腺发育不良是其最主要的两大临床表现,同时有多器官、组织受累。重组人生长激素(rhGH)和雌激素分别用于改善患者矮身材和性腺发育不良,在临床中应用广泛。近年来研究认为,在儿童早期给予rhGH联合小剂量雌激素可用于Tuner综合征的治疗。
Abstract:
Turner syndrome is a relatively common chromosomal disorder, caused by complete or partial X monosomy deletion, or structure abnormalities. Short stature and gonadal dysgenesis are two major clinical features of the syndrome, with many organs and tissues being affected. Recombinant human growth hormone(rhGH)and estrogen are applied in improving short stature and gonadal dysgenesis respectively, and widely used in clinical practice. In recent years, studies showed that rhGH combined with low-dose estrogen could be used to treat Turner syndrome.

参考文献/References:

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备注/Memo

备注/Memo:
通信作者:朱惠娟, Email: shengxin2004@163.com
更新日期/Last Update: 2017-03-20