[1]李昂,张俊清,张成,等.慢波睡眠与2型糖尿病[J].国际内分泌代谢杂志,2014,(04):267-270.[doi:10.3760/cma.j.issn.1673-4157.2014.04.015]
Li Ang*,Zhang Junqing,Zhang Cheng,et al.Relationship between slow wave sleep and type 2 diabetes[J].International Journal of Endocrinology and Metabolism,2014,(04):267-270.[doi:10.3760/cma.j.issn.1673-4157.2014.04.015]
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慢波睡眠与2型糖尿病()
《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]
- 卷:
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- 期数:
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2014年04期
- 页码:
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267-270
- 栏目:
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综述
- 出版日期:
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2014-08-31
文章信息/Info
- Title:
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Relationship between slow wave sleep and type 2 diabetes
- 作者:
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李昂; 张俊清; 张成; 马靖
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作者单位:100034 北京大学第一医院内分泌科(李昂,张俊清),呼吸和危重症科(张成,马靖)
- Author(s):
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Li Ang*; Zhang Junqing; Zhang Cheng; Ma Jing.
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*Department of Endocrinology,The First Hospital of Peking University,Beijing 100034,China
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- 关键词:
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慢波睡眠; 血糖稳态; 2型糖尿病
- Keywords:
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Slow wave sleep; Glucose homeostasis; Type 2 diabetes mellitus
- DOI:
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10.3760/cma.j.issn.1673-4157.2014.04.015
- 摘要:
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慢波睡眠减少是睡眠障碍的一个重要表现。慢波睡眠的启动伴随多种神经内分泌及代谢变化,这些变化大多与糖代谢相关。影响慢波睡眠的许多病理、生理因素亦与2型糖尿病(T2DM)发病风险增加相关。睡眠干预研究发现,慢波睡眠减少可导致糖耐量正常者胰岛素敏感性降低,交感兴奋性增加是主要原因;T2DM患者睡眠结构的一个重要变化是慢波睡眠减少,且该变化独立于呼吸睡眠障碍存在。鉴于慢波睡眠对血糖稳态的影响以及T2DM患者睡眠结构的改变,提示慢波睡眠与T2DM之间可能存在一定联系。
- Abstract:
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Reduced slow wave sleep(SWS) is a common manifestation of sleep disorders. Accompa-nied with SWS,there are a variety of neuroendocrine and metabolic changes,most of which are linked to glucose metabolism. Many physiologic and pathologic factors affecting SWS are associated with increased risk of type 2 diabetes(T2DM). Studies on sleep have found that insulin sensitivity is impaired in subjects with normal glucose tolerance after short term suppression of SWS. Increased sympathetic activity may contribute to this effect. Patients with T2DM have less time of SWS than normal subjects. This change is independent of the influence of sleep-disordered breathing. Given the impacts of SWS on glucose homeostasis,as well as changes in sleep architecture of patients with diabetes,a possible interaction may exists between SWS and diabetes.
参考文献/References:
[1] Greene R,Siegel J.Sleep:a functional enigma[J].Neuromolecular Med,2004,5(1):59-68.
[2] Cappuccio FP,D'elia L,Strazzullo P,et al.Quantity and quality of sleep and incidence of type 2 diabetes:a systematic review and meta-analysis[J].Diabetes Care,2010,33(2):414-420.
[3] Tasali E,Leproult R,Ehrmann DA,et al.Slow-wave sleep and the risk of type 2 diabetes in humans[J].Proc Natl Acad Sci U S A,2008,105(3):1044-1049.
[4] Herzog N,Jauch-Chara K,Hyzy F,et al.Selective slow wave sleep but not rapid eye movement sleep suppression impairs morning glucose tolerance in healthy men[J].Psychoneuroen-docrinology,2013,38(10):2075-2082.
[5] Stamatakis KA,Punjabi NM.Effects of sleep fragmentation on glucose metabolism in normal subjects[J].Chest,2010,137(1):95-101.
[6] Pallayova M,Donic V,Gresova S,et al.Do differences in sleep architecture exist between persons with type 2 diabetes and nondiabetic controls?[J].J Diabetes Sci Technol,2010,4(2):344-352.
[7] Steiger A.Sleep and the hypothalamo-pituitary-adrenocortical system[J].Sleep Med Rev,2002,6(2):125-138.
[8] Brandenberger G,Ehrhart J,Piquard F,et al.Inverse coupling between ultradian oscillations in delta wave activity and heart rate variability during sleep[J].Clin Neurophysiol,2001,112(6):992-996.
[9] Dang-Vu TT,Desseilles M,Laureys S,et al.Cerebral correlates of delta waves during non-REM sleep revisited[J].Neuroimage,2005,28(1):14-21.
[10] Maquet P,Dive D,Salmon E,et al.Cerebral glucose utilization during sleep-wake cycle in man determined by positron emission tomography and
[18F]2-fluoro-2-deoxy-D-glucose method[J].Brain Res,1990,513(1):136-143.
[11] Steiger,A.Sleep and endocrinology[J].J Intern Med,2003,254(1):13-22.
[12] Gronfier C,Simon C,Piquard F,et al.Neuroendocrine processes underlying ultradian sleep regulation in man[J].J Clin Endocrinol Metab,1999,84(8):2686-2690
[13] Dijk DJ.Regulation and functional correlates of slow wave sleep[J].J Clin Sleep Med,2009,5(2 Suppl):S6-S15.
[14] Rétey JV,Adam M,Honegger E,et al.A functional genetic vari-ation of adenosine deaminase affects the duration and intensity of deep sleep in humans[J].Proc Natl Acad Sci U S A,2005,102(43):15676-15681.
[15] Viola AU,Archer SN,James LM,et al.PER3 polymorphism predicts sleep structure and waking performance[J].Curr Biol,2007,17(7):613-618.
[16] Van Cauter E,Leproult R,Plat L.Age-related changes in slow wave sleep and REM sleep and relationship with growth hormone and cortisol levels in healthy men[J].JAMA,2000,284(7):861-868.
[17] Carrier J,Land S,Buysse DJ,et al.The effects of age and gender on sleep EEG power spectral density in the middle years of Life (ages 20-60 years old)[J].Psychophysiology,2001,38(2):232-242.
[18] Rao MN,Blackwell T,Redline S,et al.Association between sleep architecture and measures of body composition[J].Sleep, 2009,32(4):483-490.
[19] Levendowski DJ,Popovic D,Berka C,et al.Retrospective cross-validation of automated sleep staging using electroocular recording in patients with and without sleep disordered breathing[J].Int Arch Med, 2012,5(1):21.
[20] Krueger JM,Clinton JM,Winters BD,et al.Involvement of cy-tokines in slow wave sleep[J].Prog Brain Res,2011,193:39-47.
[21] Entzian P,Linnemann K,Schlaak M,et al.Obstructive sleep apnea syndrome and circadian rhythms of hormones and cytokines[J].Am J Respir Crit Care Med,1996,153(3):1080-1086.
[22] Krueger JM,Rector DM,Churchill L.Sleep and cytokines[J]. Sleep Med Clin,2007,2(2):161-169.
[23] Resnick HE,Redline S,Shahar E,et al.Diabetes and sleep disturbances:findings from the Sleep Heart Health Study[J].Diabetes Care, 2003,26(3):702-709.
[24] Perfect MM,Patel PG,Scott RE,et al.Sleep,glucose,and day-time functioning in youth with type 1 diabetes[J].Sleep,2012,35(1):81-88.
[25] Pillar G,Schuscheim G,Weiss R,et al.Interactions between hypoglycemia and sleep architecture in children with type 1 diabetes mellitus[J].J Pediatr,2003,142(2):163-168.
[26] Fritsche A,Stefan N,H?覿ring H,et al.Avoidance of hypoglycemia restores hypoglycemia awareness by increasing beta-adrenergic sensitivity in type 1 diabetes[J].Ann Intern Med,2001,134(9 Pt 1):729-736.
[27] Fritsche A,Stumvoll M,Grüb M,et al.Effect of hypoglycemia on beta-adrenergic sensitivity in normal and type 1 diabetic subjects[J]. Diabetes Care,1998,21(9):1505-1510.
[28] Punjabi NM,Polotsky VY.Disorders of glucose metabolism in sleep apnea[J].J Appl Physiol,2005,99(5):1998-2007.
[29] Engum A.The role of depression and anxiety in onset of diabetes in a large population-based study[J].J Psychosom Res,2007,62(1):31-38.
[30] Koren D,Levitt Katz LE,Brar PC,et al.Sleep architecture and glucose and insulin homeostasis in obese adolescents[J].Diabetes Care,2011,34(11):2442-2447.
[31] Esler M,Rumantir M,Wiesner G,et al.Sympathetic nervous system and insulin resistance:from obesity to diabetes[J].Am J Hypertens,2001,14(11 Pt 2):304S-309S.
[32] Andrews RC,Walker BR.Glucocorticoids and insulin resistance:old hormones,new targets[J].Clin Sci (Lond),1999,96(5):513-523.
[33] Weyer C,Yudkin JS,Stehouwer CD,et al.Humoral markers of inflammation and endothelial dysfunction in relation to adiposity and in vivo insulin action in Pima Indians[J].Atherosclerosis,2002,161(1):233-242.
[34] Bloomgarden TZ.Inflammation and insulin resistance[J].Diabetes Care,2003,26(5):1619-1623.
[35] Esposito K,Nappo F,Marfella R,et al.Inflammatory cytokine concentrations are acutely increased by hyperglycemia in humans:role of oxidative stress[J].Circulation,2002,106(16):2067-2072.
[36] Steer SA,Scarim AL,Chambers KT,et al.Interleukin-1 stimu-lates beta-cell necrosis and release of the immunological adjuvant HMGB1[J].PLoS Med,2006,3(2):e17.
更新日期/Last Update:
2014-07-20