[1]曹雯,郑仁东,陈国芳,等.甲状腺功能亢进症伴严重药物性胆汁郁积性肝炎1例并文献复习[J].国际内分泌代谢杂志,2014,(03):214-216.[doi:10.3760/cma.j.issn.1673-4157.2014.03.020]
　Cao Wen,Zheng Rendong,Chen Guofang,et al.One case of hyperthyroidism with severe drug-induced cholestasis hepatitis and literature review[J].International Journal of Endocrinology and Metabolism,2014,(03):214-216.[doi:10.3760/cma.j.issn.1673-4157.2014.03.020]
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甲状腺功能亢进症伴严重药物性胆汁郁积性肝炎1例并文献复习()
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《国际内分泌代谢杂志》[ISSN:1673-4157/CN:12-1383/R]

卷:
期数:
2014年03期
页码:
214-216
栏目:
病例报道
出版日期:
2014-06-30

文章信息/Info

Title:
One case of hyperthyroidism with severe drug-induced cholestasis hepatitis and literature review
作者:
曹雯; 郑仁东; 陈国芳; 包薇萍; 刘超
210028　南京,中国中医科学院江苏分院,南京中医药大学附属中西医结合医院内分泌代谢病院区 　　
Author(s):
Cao Wen; Zheng Rendong; Chen Guofang; Bao Weiping; Liu Chao.
Endocrine and Diabetes Center,Jiangsu Province Hospital on Integration of Chinese and Western Medicine,Nanjing University of Traditional Chinese Medicine,Jiangsu Branch of China Academy of Chinese Medical Science,Nanjing 210028,China Corresponding author：
关键词:
甲状腺功能亢进症; 药物性胆汁郁积性肝炎; 糖皮质激素
Keywords:
Hyperthyroidism; Drug-induced cholestasis hepatitis; Glucocorticoids
DOI:
10.3760/cma.j.issn.1673-4157.2014.03.020
摘要:
甲状腺功能亢进症（甲亢）本身可导致肝功能损害,而抗甲状腺药物亦可引起肝功能损伤。但出现严重药物性胆汁郁积性肝炎的病例比较少见,临床治疗较为困难。本院收治1例,在治疗甲亢的基础上,采用甲强龙静脉脉冲冲击联合口服强的松的方案,降低患者胆红素水平,使肝功能恢复正常,甲亢亦得以控制。
Abstract:
Hyperthyroidism can cause liver damage,while anti-thyroid drugs can also cause liver dysfunction. Severe case of drug-induced cholestasis hepatitis is rare,difficult to treat. Here we report a case with drug-induced cholestasis hepatitis. On the basis of the treatment of hyperthyroidism,intravenous methyl-prednisolone pulse therapy combined with oral prednisone was used to reduce bilirubin levels in patients,the- refore the liver function of the patient returned back to normal,and the hyperthyroidism was controlled.

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备注/Memo

备注/Memo:
通信作者：刘超,Email: liuchao@nfmcn.com
更新日期/Last Update: 2014-05-20